irritation

Unfriendly behavior that causes anger or resentment.

A sudden outburst of anger.

An uncomfortable feeling of mental painfulness or distress.

The neural or electrical arousal of an organ or muscle or gland.

The psychological state of being irritated or annoyed.

The act of troubling or annoying someone.

(pathology) abnormal sensitivity to stimulation.

“any food produced irritation of the stomach”